Droplet digital PCR for absolute quantification of proviral load of human T-cell lymphotropic virus (HTLV) types 1 and 2

High proviral load of human T cell lymphotropic virus type-1 facilitates coronary artery diseases

Objective(s): Coronary artery disease (CAD) is known as a life threatening disease, worldwide. In this study the role of HTLV-1 infection was evaluated on cardiac involvement in an endemic region of northeastern Iran.Materials and Methods: Serologic and molecular tests for HTLV-1 infection were carried out in subjects who had coronary an...

Frequency of Human T-Cell Lymphotropic Virus (HTLV) Type 1 and 2 Infection in HIV Infected Patients

Background and Objectives: Human T-cell lymphotropic viruses (HTLV) type 1 and 2 are retroviruses that share the same routes of transmission as human immunodeficiency virus (HIV). As a consequence of epidemiologic similarities, HIV and HTLV-1/2 co-infection is frequent. Due to the limited data, this study assessed the seroprevalence of HTLV-1/2 infections in HIV infected patients in Tehran, Ira...

Human T-lymphotropic Virus Type I (HTLV-I) Proviral Load and Clinical Features in Iranian HAM/TSP Patients

Awareness of laboratory students of Mashhad University of Medical Sciences about human T-cell lymphotropic virus type 1 (HTLV-1)

Introduction: HTLV-1 virus is a human retrovirus and it causes several chronic diseases. So far, there is not any vaccine or satisfactory treatment that has been developed for infections caused by this virus. Moreover, the best way to control the infection is prevention and the best way to prevent it is education. Therefore, our study was conducted to investigate the knowledge and attitudes of ...

Design a Real Time PCR with SYBR Green for quantification of HTLV-1 proviral load for blood donors

Abstract Background and Objectives In Iran, Khorasan province is an endemic area for HTLV-1 virus. Considering the inability of serological tests to determine HTLV-1 in window period, their failure to confirm the indetermination results of western blot, and given the probability for HTLV-1 transfusion transmission, a SYBR green-based Real Time PCR was set to measure the HTLV-1 proviral load.  ...